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ChEMBL ligand: CHEMBL420783 (L-740093) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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CCK1 receptor/Cholecystokinin A receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2871] [GtoPdb: 76] [UniProtKB: P30551] | ||||||||
GtoPdb | - | - | 5.8 | pKi | - | - | - | Mol Pharmacol (1994) 46: 943-8 [PMID:7969084] |
ChEMBL | Displacement of [125I]-BH CCK-8S from Cholecystokinin type A receptor in rat pancreas | B | 5.79 | pIC50 | 1604 | nM | IC50 | Bioorg. Med. Chem. Lett. (1995) 5: 3023-3026 |
ChEMBL | Inhibition of ligand binding to Cholecystokinin type A receptor from rat pancreatic tissue. | B | 5.8 | pIC50 | 1600 | nM | IC50 | J. Med. Chem. (1997) 40: 2491-2501 [PMID:9258356] |
CCK2 receptor/Cholecystokinin B receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL298] [GtoPdb: 77] [UniProtKB: P32239] | ||||||||
GtoPdb | - | - | 9.2 | pIC50 | 0.63 | nM | IC50 | Regul Pept (2002) 103: 29-37 [PMID:11738246] |
ChEMBL | Displacement of [125I]-BH CCK-8S from Cholecystokinin type B receptor in guinea pig cortex | B | 10 | pIC50 | 0.1 | nM | IC50 | Bioorg. Med. Chem. Lett. (1995) 5: 3023-3026 |
ChEMBL | Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane. | B | 10 | pIC50 | 0.1 | nM | IC50 | J. Med. Chem. (1997) 40: 2491-2501 [PMID:9258356] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]