relaxin-3 [Ligand Id: 1990] activity data from GtoPdb

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  • RXFP1 in Human [GtoPdb: 351] [UniProtKB: Q9HBX9]
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  • RXFP2 in Human [GtoPdb: 352] [UniProtKB: Q8WXD0]
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  • RXFP3 in Human [GtoPdb: 353] [UniProtKB: Q9NSD7]
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  • RXFP4 in Human [GtoPdb: 354] [UniProtKB: Q8TDU9]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
RXFP1 in Human [GtoPdb: 351] [UniProtKB: Q9HBX9]
GtoPdb - - 8 pKi - - - J Biol Chem (2003) 278: 7855-62 [PMID:12506116];
J Pharmacol Exp Ther (2005) 313: 677-87 [PMID:15649866]
RXFP2 in Human [GtoPdb: 352] [UniProtKB: Q8WXD0]
GtoPdb - - 7 pKi - - - Biochemistry (2006) 45: 1043-1053 [PMID:16411781]
RXFP3 in Human [GtoPdb: 353] [UniProtKB: Q9NSD7]
GtoPdb - - 8.92 pKi - - - J Med Chem (2012) 55: 1671-81 [PMID:22257012];
J Biol Chem (2008) 283: 17287-97 [PMID:18434306];
Mol Pharmacol (2007) 71: 1618-29 [PMID:17351017]
GtoPdb - - 9.6 pIC50 - - - J Pharmacol Exp Ther (2005) 312: 83-95 [PMID:15367576];
J Biol Chem (2003) 278: 50754-64 [PMID:14522968]
GtoPdb - - 9.93 pEC50 - - - Mol Pharmacol (2010) 77: 759-72 [PMID:20159943];
J Med Chem (2012) 55: 1671-81 [PMID:22257012];
Br J Pharmacol (2014) 171: 2827-41 [PMID:24641548];
J Biol Chem (2008) 283: 17287-97 [PMID:18434306];
Mol Pharmacol (2007) 71: 1618-29 [PMID:17351017]
RXFP4 in Human [GtoPdb: 354] [UniProtKB: Q8TDU9]
GtoPdb - - 8.83 pKi - - - J Biol Chem (2007) 282: 25425-35 [PMID:17606621];
Eur J Pharmacol (2008) 590: 43-52 [PMID:18582868]
GtoPdb - - 9 pKi - - - J Biol Chem (2003) 278: 50765-70 [PMID:14522967];
Sci Rep (2019) 9: 17828 [PMID:31780677]
GtoPdb - - 9 pIC50 - - - J Biol Chem (2007) 282: 25425-35 [PMID:17606621];
Sci Rep (2019) 9: 17828 [PMID:31780677];
Naunyn Schmiedebergs Arch Pharmacol (2017) 390: 105-111 [PMID:27888281]
GtoPdb - - 9.7 pEC50 - - - Eur J Pharmacol (2008) 590: 43-52 [PMID:18582868];
Naunyn Schmiedebergs Arch Pharmacol (2017) 390: 105-111 [PMID:27888281]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.