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ChEMBL ligand: CHEMBL427017 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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LPA1 receptor/Lysophosphatidic acid receptor Edg-2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3819] [GtoPdb: 272] [UniProtKB: Q92633] | ||||||||
ChEMBL | Activity at LPA1 receptor transfected RH7777 cells | B | 6.86 | pKi | 139 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 633-640 [PMID:16263282] |
ChEMBL | Activity at LPA1 receptor transfected RH7777 cells | B | 6.48 | pIC50 | 328 | nM | IC50 | Bioorg Med Chem Lett (2006) 16: 633-640 [PMID:16263282] |
LPA3 receptor/Lysophosphatidic acid receptor Edg-7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3250] [GtoPdb: 274] [UniProtKB: Q9UBY5] | ||||||||
ChEMBL | Activity at LPA3 receptor transfected RH7777 cells | B | 7.17 | pKi | 67 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 633-640 [PMID:16263282] |
ChEMBL | Activity at LPA3 receptor transfected RH7777 cells | B | 6.74 | pIC50 | 184 | nM | IC50 | Bioorg Med Chem Lett (2006) 16: 633-640 [PMID:16263282] |
LPA5 receptor in Rat [GtoPdb: 124] | ||||||||
GtoPdb | - | - | 5.68 | pEC50 | 2100 | nM | EC50 | J Biol Chem (2009) 284: 17304-19 [PMID:19366702] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]