omidenepag   Click here for help

GtoPdb Ligand ID: 10315

Synonyms: DE-117 (omidenepag isopropyl ophthalmic solution) | Omlonti® | UR-7276 | UR7276
Approved drug
omidenepag is an approved drug (FDA (2022))
Compound class: Synthetic organic
Comment: Omidenepag acts as a selective agonist of the prostanoid EP2 receptor [5]. It is administered as an opthalmic solution containing omidenepag isopropyl (which is named DE-117) in clinical studies [4,6]. Omidenepag isopropyl has PubChem CID 44230999.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 138.17
Molecular weight 478.14
XLogP -0.15
No. Lipinski's rules broken 0
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Canonical SMILES OC(=O)CNc1cccc(n1)CN(S(=O)(=O)c1cccnc1)Cc1ccc(cc1)n1cccn1
Isomeric SMILES OC(=O)CNc1cccc(n1)CN(S(=O)(=O)c1cccnc1)Cc1ccc(cc1)n1cccn1
InChI InChI=1S/C23H22N6O4S/c30-23(31)15-25-22-6-1-4-19(27-22)17-28(34(32,33)21-5-2-11-24-14-21)16-18-7-9-20(10-8-18)29-13-3-12-26-29/h1-14H,15-17H2,(H,25,27)(H,30,31)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (2022))
IUPAC Name Click here for help
2-[[6-[[(4-pyrazol-1-ylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]pyridin-2-yl]amino]acetic acid
International Nonproprietary Names Click here for help
INN number INN
10214 omidenepag
Synonyms Click here for help
DE-117 (omidenepag isopropyl ophthalmic solution) | Omlonti® | UR-7276 | UR7276
Database Links Click here for help
Specialist databases
GPCRdb Ligand omidenepag
Other databases
CAS Registry No. 1187451-41-7 (source: WHO INN record)
ChEMBL Ligand CHEMBL3707245
GtoPdb PubChem SID 381744996
PubChem CID 44230575
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UniChem Compound Search for chemical match using the InChIKey YHGSTSNEOJUIRN-UHFFFAOYSA-N
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