Synonyms: Ro 42-1611
Compound class:
Synthetic organic
Comment: Arteflene is a synthetic endoperoxide with antimalarial activity. It is derived from yingzhaosu A, a phytochemical endoperoxide isolated from A. uncinatus and structurally unrelated to the artemisinins [2].
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY. |
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Classification ![]() |
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Compound class | Synthetic organic |
Ligand families/groups | Antimalarial ligands |
IUPAC Name ![]() |
(1R,4S,5S,8R)-8-[(Z)-2-[2,4-bis(trifluoromethyl)phenyl]ethenyl]-4,8-dimethyl-6,7-dioxabicyclo[3.3.1]nonan-3-one |
International Nonproprietary Names ![]() |
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INN number | INN |
7168 | arteflene |
Synonyms ![]() |
Ro 42-1611 |
Database Links ![]() |
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CAS Registry No. | 123407-36-3 (source: Scifinder) |
ChEMBL Ligand | CHEMBL380230 |
GtoPdb PubChem SID | 384403676 |
PubChem CID | 6436134 |
Search Google for chemical match using the InChIKey | LRTRTVPZZJAADL-DAHZFVMQSA-N |
Search Google for chemicals with the same backbone | LRTRTVPZZJAADL |
Search PubMed clinical trials | arteflene |
Search PubMed titles | arteflene |
Search PubMed titles/abstracts | arteflene |
UniChem Compound Search for chemical match using the InChIKey | LRTRTVPZZJAADL-DAHZFVMQSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | LRTRTVPZZJAADL-DAHZFVMQSA-N |