BzT-7 [Ligand Id: 7515] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1958337 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| bromodomain containing 4/Bromodomain-containing protein 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1163125] [GtoPdb: 1945] [UniProtKB: O60885] | ||||||||
| GtoPdb | Measuring the dissociation constant for the compound's interaction with BD1 of BRD4. | - | 6.19 | pKd | 640 | nM | Kd | Bioorg Med Chem (2012) 20: 1878-86 [PMID:22137933] |
| ChEMBL | Binding affinity to BRD4-BD1 by isothermal titration calorimetry | B | 6.19 | pKd | 640 | nM | Kd | Bioorg Med Chem (2012) 20: 1878-1886 [PMID:22137933] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
