Synonyms: (S)-17 [PMID: 31790581] | UCM05194
Compound class:
Synthetic organic
Comment: UCM-05194 (compound (S)-17) is a LPA1 receptor agonist [1]. UCM-05194-mediated internalisation of the receptor induces functional inactivation of LPA1 cellular effects in vitro, which translates to attenuation of pain perception in an animal model of neuropathic pain. It is therefore a suitable tool for assessing LPA1-mediated effects in vitro and for evaluating the potential of in vivo LPA1 receptor modulation as a strategy for therapeutic intervention in neuropathic pain.
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Classification ![]() |
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Compound class | Synthetic organic |
IUPAC Name ![]() |
(2S)-1-Bromo-3-(phosphonooxy)propan-2-yl 10-Phenyldecanoate |
Synonyms ![]() |
(S)-17 [PMID: 31790581] | UCM05194 |
Database Links ![]() |
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Specialist databases | |
GPCRdb Ligand | UCM-05194 |
Other databases | |
GtoPdb PubChem SID | 404859034 |
PubChem CID | 145996523 |
Search Google for chemical match using the InChIKey | IHTMTVSBHMPLJC-GOSISDBHSA-N |
Search Google for chemicals with the same backbone | IHTMTVSBHMPLJC |
UniChem Compound Search for chemical match using the InChIKey | IHTMTVSBHMPLJC-GOSISDBHSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | IHTMTVSBHMPLJC-GOSISDBHSA-N |