Synonyms: RDEA-3170 | RDEA3170
Compound class:
Synthetic organic
Comment: Verinurad (RDEA3170) is an investigational selective uric acid reabsorption inhibitor, functionally inhibiting the URAT1 (SLC22A12) transporter and being investigated for clinical efficacy in controlling uric acid levels in patients with gout. URAT1 is the renal transporter that regulates uric acid excretion from the body. Verinurad is structurally related to lesinurad (RDEA594), a URAT1 inhibitor already approved for treating hyperuricemia in gout.
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
2-[3-(4-cyanonaphthalen-1-yl)pyridin-4-yl]sulfanyl-2-methylpropanoic acid |
International Nonproprietary Names | |
INN number | INN |
9938 | verinurad |
Synonyms |
RDEA-3170 | RDEA3170 |
Database Links | |
CAS Registry No. | 1352792-74-5 (source: WHO INN record) |
GtoPdb PubChem SID | 318164846 |
PubChem CID | 54767229 |
RCSB PDB Ligand | A1AIJ |
Search Google for chemical match using the InChIKey | YYBOLPLTQDKXPM-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | YYBOLPLTQDKXPM |
Search PubMed clinical trials | verinurad |
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Search PubMed titles/abstracts | verinurad |
UniChem Compound Search for chemical match using the InChIKey | YYBOLPLTQDKXPM-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | YYBOLPLTQDKXPM-UHFFFAOYSA-N |