solriamfetol   Click here for help

GtoPdb Ligand ID: 10342

Synonyms: ADX-N05 | ADXN05 | JZP-110 | JZP110 | Sunosi®
Approved drug
solriamfetol is an approved drug (FDA (2019), EMA (2020))
Compound class: Synthetic organic
Comment: Solriamfetol is a norepinephrine-dopamine reuptake inhibitor that was developed by Jazz Pharmaceuticals [1].
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 78.34
Molecular weight 194.11
XLogP 0.49
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES NC(Cc1ccccc1)COC(=O)N
Isomeric SMILES N[C@H](Cc1ccccc1)COC(=O)N
InChI InChI=1S/C10H14N2O2/c11-9(7-14-10(12)13)6-8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H2,12,13)/t9-/m1/s1
InChI Key UCTRAOBQFUDCSR-SECBINFHSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (2019), EMA (2020))
IUPAC Name Click here for help
[(2R)-2-amino-3-phenylpropyl] carbamate
International Nonproprietary Names Click here for help
INN number INN
10117 solriamfetol
Synonyms Click here for help
ADX-N05 | ADXN05 | JZP-110 | JZP110 | Sunosi®
Database Links Click here for help
CAS Registry No. 178429-62-4 (source: WHO INN record)
DrugCentral Ligand 5325
GtoPdb PubChem SID 381745023
PubChem CID 10130337
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