sertindole   Click here for help

GtoPdb Ligand ID: 98

Synonyms: Serdolect® | Serlect® | sertindol
Approved drug
sertindole is an approved drug
Compound class: Synthetic organic
Comment: Sertindole is an atypical antipsychotic medication, functioning as a dopamine D2 and serotonin 5-HT2 receptor antagonist.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 39.99
Molecular weight 440.18
XLogP 4.14
No. Lipinski's rules broken 0
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Canonical SMILES Clc1ccc2c(c1)c(cn2c1ccc(cc1)F)C1CCN(CC1)CCN1CCNC1=O
Isomeric SMILES Clc1ccc2c(c1)c(cn2c1ccc(cc1)F)C1CCN(CC1)CCN1CCNC1=O
InChI InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
Withdrawn drug? Yes
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
6455 sertindole
Synonyms Click here for help
Serdolect® | Serlect® | sertindol
Database Links Click here for help
Specialist databases
GPCRdb Ligand sertindole
Other databases
BindingDB Ligand 50001786
CAS Registry No. 106516-24-9
ChEMBL Ligand CHEMBL12713
DrugBank Ligand DB06144
DrugCentral Ligand 2435
GtoPdb PubChem SID 135651037
PubChem CID 60149
Search Google for chemical match using the InChIKey GZKLJWGUPQBVJQ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GZKLJWGUPQBVJQ
Search PubMed clinical trials sertindole
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UniChem Compound Search for chemical match using the InChIKey GZKLJWGUPQBVJQ-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey GZKLJWGUPQBVJQ-UHFFFAOYSA-N
Wikipedia Sertindole