ustekinumab   Click here for help

GtoPdb Ligand ID: 6885

Synonyms: CNTO-1275 | L04AC05 | Stelara® | TT-20
Approved drug Immunopharmacology Ligand
ustekinumab is an approved drug (FDA (2009), EMA (2009))
Compound class: Antibody
Comment: Ustekinumab suppresses the immunomodulatory actions of both IL-12 and IL-23 on T-cell sub-populations. It binds to the common p40 subunit (IL12B) shared by these cytokines.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.

NameTrade nameCompanyClinical PhaseIndications
ustekinumab-auub; ABP 654WezlanaAmgenApproved (2023 FDA)As per reference agent; Interchangeable with reference agent
ustekinumab-aekn; AVT04SelarsdiAlvotech/Teva PharmaceuticalsApproved (2024 FDA)As per reference agent
Classification Click here for help
Compound class Antibody
Approved drug? Yes (FDA (2009), EMA (2009))
International Nonproprietary Names Click here for help
INN number INN
8954 ustekinumab
Synonyms Click here for help
CNTO-1275 | L04AC05 | Stelara® | TT-20
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 172
Other databases
GtoPdb PubChem SID 178103467
PubChem SID 178103467
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Wikipedia Ustekinumab