Ligand id: 6885

Name: ustekinumab

No information available.
Summary of Clinical Use
Used to treat adult patients (18 years or older) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy and is approved in the US to treat psoriatic arthritis.
Mechanism Of Action and Pharmacodynamic Effects
Ustekinumab binds to the IL-12B component of the dimeric cytokines IL-12 and IL-23. This action supresses the activation of certain T-cells, thereby dampening the immune response.
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