Ligand id: 6885

Name: ustekinumab

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
The patent covering the production and use of ustekinumab (US6902734 [1]) does not provide affinity values for specific antibody clones, therefore we have included the stated range of affinities determined in the production and testing process in the interaction table below..
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
IL-12B Hs Antibody Inhibition >9.0 – 11.1 pKd - 1
pKd >9.0 – 11.1 (Kd <1x10-9 – 7x10-12 M) [1]