Ligand id: 6885

Name: ustekinumab

Compound class Antibody
Approved drug? Yes (FDA (2009), EMA (2009))
International Nonproprietary Names
INN number INN
8954 ustekinumab
CNTO-1275 | L04AC05 | Stelara® | TT-20
Ustekinumab suppresses the immunomodulatory actions of both IL-12 and IL-23 on T-cell sub-populations. It binds to the common p40 subunit (IL12B) shared by these cytokines.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Qyuns Therapeutics have a potential ustekinumab biosimilar (QX001S) in Phase 1 evaluation for psoriasis (trial registry number ChiCTR1900022127).
Database Links
Specialist databases
IMGT/mAb-DB 172
Other databases
GtoPdb PubChem SID 178103467
PubChem SID 178103467
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Wikipedia Ustekinumab