ChEMBL ligand: CHEMBL426445
ribosomal protein S6 kinase B2/Ribosomal protein S6 kinase 2 in Human [ChEMBL: CHEMBL3111] [GtoPdb: 1526] [UniProtKB: Q9UBS0] There should be some charts here, you may need to enable JavaScript!
SRSF protein kinase 1/Serine/threonine-protein kinase SRPK1 in Human [ChEMBL: CHEMBL4375] [GtoPdb: 2208] [UniProtKB: Q96SB4] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
ribosomal protein S6 kinase B2/Ribosomal protein S6 kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3111] [GtoPdb: 1526] [UniProtKB: Q9UBS0]
ChEMBL	In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphate	B	7.4	pIC50	40	nM	IC50	Bioorg Med Chem Lett (2005) 15: 3241-3246 [PMID:15925511]
SRSF protein kinase 1/Serine/threonine-protein kinase SRPK1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4375] [GtoPdb: 2208] [UniProtKB: Q96SB4]
ChEMBL	Inhibition of SRPK1 kinase (unknown origin)	B	7.4	pIC50	40	nM	IC50	Eur J Med Chem (2014) 85: 688-715 [PMID:25128670]
GtoPdb	-	-	7.4	pIC50	40	nM	IC50	Bioorg Med Chem Lett (2005) 15: 3241-6 [PMID:15925511]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]