moexipril [Ligand Id: 6571] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1165 (Moexipril, RS-10085, Uniretic, Univasc)
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Angiotensin-converting enzyme in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1808] [GtoPdb: 1613] [UniProtKB: P12821]
ChEMBL Inhibition of guinea pig angiotensin I converting enzyme B 7.25 pIC50 56 nM IC50 J. Med. Chem. (1986) 29: 1953-1961 [PMID:3020249]
ChEMBL Inhibitory activity against angiotensin I converting enzyme (ACE) B 8.59 pIC50 2.6 nM IC50 J. Med. Chem. (2000) 43: 305-341 [PMID:10669559]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]