ChEMBL ligand: CHEMBL2153161
cathepsin B/Cathepsin B in Human [ChEMBL: CHEMBL4072] [GtoPdb: 2343] [UniProtKB: P07858] There should be some charts here, you may need to enable JavaScript!
cathepsin F/Cathepsin F in Human [ChEMBL: CHEMBL2517] [GtoPdb: 2347] [UniProtKB: Q9UBX1] There should be some charts here, you may need to enable JavaScript!
cathepsin K/Cathepsin K in Human [ChEMBL: CHEMBL268] [GtoPdb: 2350] [UniProtKB: P43235] There should be some charts here, you may need to enable JavaScript!
cathepsin L/Cathepsin L in Human [ChEMBL: CHEMBL3837] [GtoPdb: 2351] [UniProtKB: P07711] There should be some charts here, you may need to enable JavaScript!
cathepsin S/Cathepsin S in Human [ChEMBL: CHEMBL2954] [GtoPdb: 2353] [UniProtKB: P25774] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
cathepsin B/Cathepsin B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4072] [GtoPdb: 2343] [UniProtKB: P07858]
ChEMBL	Inhibition of human cathepsin B using Z-Arg-Arg-pNA as substrate after 80 mins by spectrophotometric analysis	B	8.24	pKi	5.8	nM	Ki	J Med Chem (2012) 55: 5982-5986 [PMID:22686657]
cathepsin F/Cathepsin F in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2517] [GtoPdb: 2347] [UniProtKB: Q9UBX1]
ChEMBL	Inhibition of human recombinant cathepsin F using Z-Phe-Arg-AMC as substrate by fluorimetric analysis	B	7.68	pKi	21	nM	Ki	J Med Chem (2012) 55: 5982-5986 [PMID:22686657]
GtoPdb	-	-	7.68	pKi	21	nM	Ki	J Med Chem (2012) 55: 5982-6 [PMID:22686657]
cathepsin K/Cathepsin K in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL268] [GtoPdb: 2350] [UniProtKB: P43235]
ChEMBL	Inhibition of human cathepsin K using Z-Leu-Arg-AMC as substrate after 80 mins by fluorimetric analysis	B	9.18	pKi	0.66	nM	Ki	J Med Chem (2012) 55: 5982-5986 [PMID:22686657]
cathepsin L/Cathepsin L in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3837] [GtoPdb: 2351] [UniProtKB: P07711]
ChEMBL	Inhibition of human cathepsin L using Z-Phe-Arg-pNA as substrate after 80 mins by spectrophotometric analysis	B	7.82	pKi	15	nM	Ki	J Med Chem (2012) 55: 5982-5986 [PMID:22686657]
cathepsin S/Cathepsin S in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2954] [GtoPdb: 2353] [UniProtKB: P25774]
ChEMBL	Inhibition of human cathepsin S using Z-Phe-Val-Arg-pNA as substrate after 80 mins by spectrophotometric analysis	B	9.26	pKi	0.55	nM	Ki	J Med Chem (2012) 55: 5982-5986 [PMID:22686657]
GtoPdb	-	-	9.3	pKi	0.55	nM	Ki	J Med Chem (2012) 55: 5982-6 [PMID:22686657]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]