PSB-6426 [Ligand Id: 9033] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL469212 (PSB-6426)
  • ectonucleoside triphosphate diphosphohydrolase 2/Ectonucleoside triphosphate diphosphohydrolase 2 in Human [ChEMBL: CHEMBL5049] [GtoPdb: 2889] [UniProtKB: Q9Y5L3]
  • 5.09
1 CHEMBL469212_lig_chart_1 Ectonucleoside triphosphate diphosphohydrolase 2 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ectonucleoside triphosphate diphosphohydrolase 2/Ectonucleoside triphosphate diphosphohydrolase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5049] [GtoPdb: 2889] [UniProtKB: Q9Y5L3]
ChEMBL Inhibition of human NTPDase 2 expressed in HEK293 cells B 5.09 pKi 8200 nM Ki J. Med. Chem. (2008) 51: 4518-4528 [PMID:18630897]
GtoPdb - - 5.09 pKi 8200 nM Ki J Med Chem (2008) 51: 4518-28 [PMID:18630897]
ChEMBL Inhibition of human NTPDase 2 expressed in HEK293 cells assessed as residual activity by capillary electrophoresis B 4.38 pIC50 42000 nM IC50 J. Med. Chem. (2008) 51: 4518-4528 [PMID:18630897]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]