Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	2	495	9q34.3	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	3
Mouse	2	495	2 A3	Entpd2	ectonucleoside triphosphate diphosphohydrolase 2
Rat	2	495	3p13	Entpd2	ectonucleoside triphosphate diphosphohydrolase 2

Previous and Unofficial Names

CD39 antigen-like 1 | CD39L1 | ecto-ATPase 2 | NTPDase 2 | NTPDase-2

Database Links
Alphafold	Q9Y5L3 (Hs), O55026 (Mm), O35795 (Rn)
BRENDA	3.6.1.-
ChEMBL Target	CHEMBL5049 (Hs), CHEMBL3300 (Rn)
Ensembl Gene	ENSG00000054179 (Hs), ENSMUSG00000015085 (Mm), ENSRNOG00000013102 (Rn)
Entrez Gene	954 (Hs), 12496 (Mm), 64467 (Rn)
Human Protein Atlas	ENSG00000054179 (Hs)
KEGG Enzyme	3.6.1.-
KEGG Gene	hsa:954 (Hs), mmu:12496 (Mm), rno:64467 (Rn)
OMIM	602012 (Hs)
Pharos	Q9Y5L3 (Hs)
RefSeq Nucleotide	NM_203468 (Hs), NM_009849 (Mm), NM_172030 (Rn)
RefSeq Protein	NP_982293 (Hs), NP_033979 (Mm), NP_742027 (Rn)
UniProtKB	Q9Y5L3 (Hs), O55026 (Mm), O35795 (Rn)
Wikipedia	ENTPD2 (Hs)

Enzyme Reaction
EC Number: 3.6.1.- Description Reaction Reference Hydrolyzes extracellular nucleotide 5'-triphosphates NTP>NMP + 2 phosphate

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Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference PSB-6426 Hs Inhibition 5.1 pKi 1 ⤷ pKi 5.1 (Ki 8.2x10-6 M) [1]

Immuno Process Associations

Immuno Process:  Cytokine production & signalling

General Comments
ENTPD2 preferentially hydrolyses nucleoside triphosphates over nucleoside diphosphates [2-3].