Synonyms: gamma-Secretase Inhibitor IX | GSI-IX | LY-374973
Compound class:
Synthetic organic
Comment: DAPT is a γ-secretase inhibitor [1] that is used experimentally to inhibit NOTCH pathway signalling. Chemically it is a modified di-peptide (IUPAC Condensed name Unk-Ala-Phg-OtBu).
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Classification ![]() |
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Compound class | Synthetic organic |
IUPAC Name ![]() |
tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate |
Synonyms ![]() |
gamma-Secretase Inhibitor IX | GSI-IX | LY-374973 |
Database Links ![]() |
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ChEMBL Ligand | CHEMBL255682 |
GtoPdb PubChem SID | 440816732 |
PubChem CID | 5311272 |
Search Google for chemical match using the InChIKey | DWJXYEABWRJFSP-XOBRGWDASA-N |
Search Google for chemicals with the same backbone | DWJXYEABWRJFSP |
UniChem Compound Search for chemical match using the InChIKey | DWJXYEABWRJFSP-XOBRGWDASA-N |
UniChem Connectivity Search for chemical match using the InChIKey | DWJXYEABWRJFSP-XOBRGWDASA-N |