CL316243 [Ligand Id: 3462] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL1204876 (CL-316243)
  • β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945]
  • β3-adrenoceptor in Mouse [GtoPdb: 30] [UniProtKB: P25962]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945]
GtoPdb - - 5.2 pKi - - - Tohoku J Exp Med (2000) 192: 181-93 [PMID:11249148]
β3-adrenoceptor in Mouse [GtoPdb: 30] [UniProtKB: P25962]
GtoPdb - - 5.9 pKi - - Ki Mol Pharmacol (2007) 72: 1359-68 [PMID:17717109]
GtoPdb - - 9.8 pEC50 - - - Mol Pharmacol (2007) 72: 1359-68 [PMID:17717109];
Naunyn Schmiedebergs Arch Pharmacol (2006) 373: 158-68 [PMID:16601951]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]