Dooku1

Ligand id: 10112

Name: Dooku1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 80.01
Molecular weight 324.98
XLogP 5.14
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[(2,6-Dichlorobenzyl)thio)-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole
Synonyms
Dooku 1 | Dooku-1
Comments
Dooku 1 blocks Yoda1-induced activation of Piezo1 ion channels [1]. It has no effect on constitutive Piezo1 activity.
Database Links
GtoPdb PubChem SID 381118822
Search Google for chemical match using the InChIKey MNPOBXLPCWFONX-UHFFFAOYSA-N
Search Google for chemicals with the same backbone MNPOBXLPCWFONX
Search UniChem for chemical match using the InChIKey MNPOBXLPCWFONX-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone MNPOBXLPCWFONX