FRAX597 [Ligand Id: 8939] activity data from GtoPdb

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  • p21 (RAC1) activated kinase 1 in Human [GtoPdb: 2133] [UniProtKB: Q13153]
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  • p21 (RAC1) activated kinase 2 in Human [GtoPdb: 2134] [UniProtKB: Q13177]
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  • p21 (RAC1) activated kinase 3 in Human [GtoPdb: 2135] [UniProtKB: O75914]
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  • p21 (RAC1) activated kinase 4 in Human [GtoPdb: 2136] [UniProtKB: O96013]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
p21 (RAC1) activated kinase 1 in Human [GtoPdb: 2133] [UniProtKB: Q13153]
GtoPdb - - 8.1 pIC50 8 nM IC50 J Biol Chem (2013) 288: 29105-14 [PMID:23960073]
p21 (RAC1) activated kinase 2 in Human [GtoPdb: 2134] [UniProtKB: Q13177]
GtoPdb - - 7.89 pIC50 13 nM IC50 J Biol Chem (2013) 288: 29105-14 [PMID:23960073]
p21 (RAC1) activated kinase 3 in Human [GtoPdb: 2135] [UniProtKB: O75914]
GtoPdb - - 7.72 pIC50 19 nM IC50 J Biol Chem (2013) 288: 29105-14 [PMID:23960073]
p21 (RAC1) activated kinase 4 in Human [GtoPdb: 2136] [UniProtKB: O96013]
GtoPdb - - 5 pIC50 >10000 nM IC50 J Biol Chem (2013) 288: 29105-14 [PMID:23960073]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.