Ligand id: 7397
Name: ceritinib
View more information in the IUPHAR Pharmacology Education Project: ceritinib
|
Molecular properties generated using the CDK |
Classification ![]() |
|
Compound class | Synthetic organic |
Approved drug? | Yes (FDA (2014), EMA (2015)) |
IUPAC Name ![]() |
5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine |
International Nonproprietary Names ![]() |
|
INN number | INN |
9817 | ceritinib |
Synonyms ![]() |
compound 15b [PMID 23742252] | LDK378 | NVP-LDK378-NX | Zykadia® |
Comments |
Ceritinib is a novel, highly selective, second generation ALK inhibitor [2]. |
Database Links ![]() |
|
CAS Registry No. | 1032900-25-6 |
ChEMBL Ligand | CHEMBL2403108 |
GtoPdb PubChem SID | 178103969 |
PubChem CID | 57379345 |
RCSB PDB Ligand | 4MK |
Search Google for chemical match using the InChIKey | VERWOWGGCGHDQE-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | VERWOWGGCGHDQE |
Search PubMed clinical trials | ceritinib |
Search PubMed titles | ceritinib |
Search PubMed titles/abstracts | ceritinib |
Search UniChem for chemical match using the InChIKey | VERWOWGGCGHDQE-UHFFFAOYSA-N |
Search UniChem for chemicals with the same backbone | VERWOWGGCGHDQE |
SynPHARM | 79503 (in complex with anaplastic lymphoma receptor tyrosine kinase) |
Wikipedia | Ceritinib |