Classification
Compound class	Synthetic organic
Approved drug?	Yes (FDA (2014), EMA (2015))

IUPAC Name

5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine

International Nonproprietary Names
INN number	INN
9817	ceritinib

Synonyms

compound 15b [PMID 23742252] | LDK378 | NVP-LDK378-NX | Zykadia®

Comments

Ceritinib is a novel, highly selective, second generation ALK inhibitor [2].

Database Links
CAS Registry No.	1032900-25-6
ChEMBL Ligand	CHEMBL2403108
GtoPdb PubChem SID	178103969
PubChem CID	57379345
RCSB PDB Ligand	4MK
Search Google for chemical match using the InChIKey	VERWOWGGCGHDQE-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	VERWOWGGCGHDQE
Search PubMed clinical trials	ceritinib
Search PubMed titles	ceritinib
Search PubMed titles/abstracts	ceritinib
Search UniChem for chemical match using the InChIKey	VERWOWGGCGHDQE-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	VERWOWGGCGHDQE
SynPHARM	79503 (in complex with anaplastic lymphoma receptor tyrosine kinase)
Wikipedia	Ceritinib