A-803467 [Ligand Id: 5734] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL250699 (A-803467)
  • A1 receptor/Adenosine A1 receptor in Human [ChEMBL: CHEMBL226] [GtoPdb: 18] [UniProtKB: P30542]
  • This target only has 0 pki data point
  • 0
1 CHEMBL250699_lig_chart_1 Adenosine A1 receptor Human
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  • A2A receptor/Adenosine A2a receptor in Human [ChEMBL: CHEMBL251] [GtoPdb: 19] [UniProtKB: P29274]
  • This target only has 0 pki data point
  • 0
2 CHEMBL250699_lig_chart_2 Adenosine A2a receptor Human
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  • A3 receptor/Adenosine A3 receptor in Human [ChEMBL: CHEMBL256] [GtoPdb: 21] [UniProtKB: P0DMS8]
  • This target only has 0 pki data point
  • 0
3 CHEMBL250699_lig_chart_3 Adenosine A3 receptor Human
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  • α1B-adrenoceptor/Alpha-1b adrenergic receptor in Human [ChEMBL: CHEMBL232] [GtoPdb: 23] [UniProtKB: P35368]
  • This target only has 0 pki data point
  • 0
4 CHEMBL250699_lig_chart_4 Alpha-1b adrenergic receptor Human
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  • α2A-adrenoceptor/Alpha-2a adrenergic receptor in Human [ChEMBL: CHEMBL1867] [GtoPdb: 25] [UniProtKB: P08913]
  • This target only has 0 pki data point
  • 0
5 CHEMBL250699_lig_chart_5 Alpha-2a adrenergic receptor Human
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  • α2B-adrenoceptor/Alpha-2b adrenergic receptor in Human [ChEMBL: CHEMBL1942] [GtoPdb: 26] [UniProtKB: P18089]
  • This target only has 0 pki data point
  • 0
6 CHEMBL250699_lig_chart_6 Alpha-2b adrenergic receptor Human
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  • CB1 receptor/Cannabinoid CB1 receptor in Human [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554]
  • This target only has 0 pki data point
  • 0
7 CHEMBL250699_lig_chart_7 Cannabinoid CB1 receptor Human
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  • CB2 receptor/Cannabinoid CB2 receptor in Human [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972]
  • This target only has 0 pki data point
  • 0
8 CHEMBL250699_lig_chart_8 Cannabinoid CB2 receptor Human
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  • CCR1/C-C chemokine receptor type 1 in Human [ChEMBL: CHEMBL2413] [GtoPdb: 58] [UniProtKB: P32246]
  • This target only has 0 pki data point
  • 0
9 CHEMBL250699_lig_chart_9 C-C chemokine receptor type 1 Human
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  • CCK1 receptor/Cholecystokinin A receptor in Human [ChEMBL: CHEMBL1901] [GtoPdb: 76] [UniProtKB: P32238]
  • This target only has 0 pki data point
  • 0
10 CHEMBL250699_lig_chart_10 Cholecystokinin A receptor Human
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  • δ receptor/Delta opioid receptor in Human [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143]
  • This target only has 0 pki data point
  • 0
11 CHEMBL250699_lig_chart_11 Delta opioid receptor Human
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  • D1 receptor/Dopamine D1 receptor in Human [ChEMBL: CHEMBL2056] [GtoPdb: 214] [UniProtKB: P21728]
  • This target only has 0 pki data point
  • 0
12 CHEMBL250699_lig_chart_12 Dopamine D1 receptor Human
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  • D2 receptor/Dopamine D2 receptor in Human [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416]
  • This target only has 0 pki data point
  • 0
13 CHEMBL250699_lig_chart_13 Dopamine D2 receptor Human
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  • D3 receptor/Dopamine D3 receptor in Human [ChEMBL: CHEMBL234] [GtoPdb: 216] [UniProtKB: P35462]
  • This target only has 0 pki data point
  • 0
14 CHEMBL250699_lig_chart_14 Dopamine D3 receptor Human
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  • D4 receptor/Dopamine D4 receptor in Human [ChEMBL: CHEMBL219] [GtoPdb: 217] [UniProtKB: P21917]
  • This target only has 0 pki data point
  • 0
15 CHEMBL250699_lig_chart_15 Dopamine D4 receptor Human
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  • D5 receptor/Dopamine D5 receptor in Human [ChEMBL: CHEMBL1850] [GtoPdb: 218] [UniProtKB: P21918]
  • This target only has 0 pki data point
  • 0
16 CHEMBL250699_lig_chart_16 Dopamine D5 receptor Human
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  • ETA receptor/Endothelin receptor ET-A in Human [ChEMBL: CHEMBL252] [GtoPdb: 219] [UniProtKB: P25101]
  • This target only has 0 pki data point
  • 0
17 CHEMBL250699_lig_chart_17 Endothelin receptor ET-A Human
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  • H1 receptor/Histamine H1 receptor in Human [ChEMBL: CHEMBL231] [GtoPdb: 262] [UniProtKB: P35367]
  • This target only has 0 pki data point
  • 0
18 CHEMBL250699_lig_chart_18 Histamine H1 receptor Human
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  • H2 receptor/Histamine H2 receptor in Human [ChEMBL: CHEMBL1941] [GtoPdb: 263] [UniProtKB: P25021]
  • This target only has 0 pki data point
  • 0
19 CHEMBL250699_lig_chart_19 Histamine H2 receptor Human
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  • CXCR2/Interleukin-8 receptor B in Human [ChEMBL: CHEMBL2434] [GtoPdb: 69] [UniProtKB: P25025]
  • This target only has 0 pki data point
  • 0
20 CHEMBL250699_lig_chart_20 Interleukin-8 receptor B Human
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  • κ receptor/Kappa opioid receptor in Human [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145]
  • This target only has 0 pki data point
  • 0
21 CHEMBL250699_lig_chart_21 Kappa opioid receptor Human
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  • μ receptor/Mu opioid receptor in Human [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372]
  • This target only has 0 pki data point
  • 0
22 CHEMBL250699_lig_chart_22 Mu opioid receptor Human
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  • M1 receptor/Muscarinic acetylcholine receptor M1 in Human [ChEMBL: CHEMBL216] [GtoPdb: 13] [UniProtKB: P11229]
  • This target only has 0 pki data point
  • 0
23 CHEMBL250699_lig_chart_23 Muscarinic acetylcholine receptor M1 Human
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  • M2 receptor/Muscarinic acetylcholine receptor M2 in Human [ChEMBL: CHEMBL211] [GtoPdb: 14] [UniProtKB: P08172]
  • This target only has 0 pki data point
  • 0
24 CHEMBL250699_lig_chart_24 Muscarinic acetylcholine receptor M2 Human
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  • M3 receptor/Muscarinic acetylcholine receptor M3 in Human [ChEMBL: CHEMBL245] [GtoPdb: 15] [UniProtKB: P20309]
  • This target only has 0 pki data point
  • 0
25 CHEMBL250699_lig_chart_25 Muscarinic acetylcholine receptor M3 Human
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  • M4 receptor/Muscarinic acetylcholine receptor M4 in Human [ChEMBL: CHEMBL1821] [GtoPdb: 16] [UniProtKB: P08173]
  • This target only has 0 pki data point
  • 0
26 CHEMBL250699_lig_chart_26 Muscarinic acetylcholine receptor M4 Human
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  • M5 receptor/Muscarinic acetylcholine receptor M5 in Human [ChEMBL: CHEMBL2035] [GtoPdb: 17] [UniProtKB: P08912]
  • This target only has 0 pki data point
  • 0
27 CHEMBL250699_lig_chart_27 Muscarinic acetylcholine receptor M5 Human
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  • NOP receptor/Nociceptin receptor in Human [ChEMBL: CHEMBL2014] [GtoPdb: 320] [UniProtKB: P41146]
  • This target only has 0 pki data point
  • 0
28 CHEMBL250699_lig_chart_28 Nociceptin receptor Human
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  • P2X2/P2X purinoceptor 2 in Human [ChEMBL: CHEMBL2531] [GtoPdb: 479] [UniProtKB: Q9UBL9]
  • This target only has 0 pki data point
  • 0
29 CHEMBL250699_lig_chart_29 P2X purinoceptor 2 Human
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  • P2X3/P2X purinoceptor 3 in Human [ChEMBL: CHEMBL2998] [GtoPdb: 480] [UniProtKB: P56373]
  • This target only has 0 pki data point
  • 0
30 CHEMBL250699_lig_chart_30 P2X purinoceptor 3 Human
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  • P2Y2 receptor/Purinergic receptor P2Y2 in Human [ChEMBL: CHEMBL4398] [GtoPdb: 324] [UniProtKB: P41231]
  • This target only has 0 pki data point
  • 0
31 CHEMBL250699_lig_chart_31 Purinergic receptor P2Y2 Human
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  • 5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Human [ChEMBL: CHEMBL214] [GtoPdb: 1] [UniProtKB: P08908]
  • This target only has 0 pki data point
  • 0
32 CHEMBL250699_lig_chart_32 Serotonin 1a (5-HT1a) receptor Human
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  • 5-HT1B receptor/Serotonin 1b (5-HT1b) receptor in Human [ChEMBL: CHEMBL1898] [GtoPdb: 2] [UniProtKB: P28222]
  • This target only has 0 pki data point
  • 0
33 CHEMBL250699_lig_chart_33 Serotonin 1b (5-HT1b) receptor Human
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  • 5-HT2A receptor/Serotonin 2a (5-HT2a) receptor in Human [ChEMBL: CHEMBL224] [GtoPdb: 6] [UniProtKB: P28223]
  • This target only has 0 pki data point
  • 0
34 CHEMBL250699_lig_chart_34 Serotonin 2a (5-HT2a) receptor Human
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  • 5-HT2C receptor/Serotonin 2c (5-HT2c) receptor in Human [ChEMBL: CHEMBL225] [GtoPdb: 8] [UniProtKB: P28335]
  • This target only has 0 pki data point
  • 0
35 CHEMBL250699_lig_chart_35 Serotonin 2c (5-HT2c) receptor Human
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  • 5-HT3A/Serotonin 3a (5-HT3a) receptor in Human [ChEMBL: CHEMBL1899] [GtoPdb: 373] [UniProtKB: P46098]
  • This target only has 0 pki data point
  • 0
36 CHEMBL250699_lig_chart_36 Serotonin 3a (5-HT3a) receptor Human
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  • 5-HT5A receptor/Serotonin 5a (5-HT5a) receptor in Human [ChEMBL: CHEMBL3426] [GtoPdb: 10] [UniProtKB: P47898]
  • This target only has 0 pki data point
  • 0
37 CHEMBL250699_lig_chart_37 Serotonin 5a (5-HT5a) receptor Human
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  • 5-HT6 receptor/Serotonin 6 (5-HT6) receptor in Human [ChEMBL: CHEMBL3371] [GtoPdb: 11] [UniProtKB: P50406]
  • This target only has 0 pki data point
  • 0
38 CHEMBL250699_lig_chart_38 Serotonin 6 (5-HT6) receptor Human
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  • 5-HT7 receptor/Serotonin 7 (5-HT7) receptor in Human [ChEMBL: CHEMBL3155] [GtoPdb: 12] [UniProtKB: P34969]
  • This target only has 0 pki data point
  • 0
39 CHEMBL250699_lig_chart_39 Serotonin 7 (5-HT7) receptor Human
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  • sigma non-opioid intracellular receptor 1/Sigma opioid receptor in Human [ChEMBL: CHEMBL287] [GtoPdb: 2552] [UniProtKB: Q99720]
  • This target only has 0 pki data point
  • 0
40 CHEMBL250699_lig_chart_40 Sigma opioid receptor Human
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  • Nav1.2/Sodium channel protein type II alpha subunit in Human [ChEMBL: CHEMBL4187] [GtoPdb: 579] [UniProtKB: Q99250]
  • This target only has 0 pki data point
  • 0
41 CHEMBL250699_lig_chart_41 Sodium channel protein type II alpha subunit Human
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  • Nav1.3/Sodium channel protein type III alpha subunit in Human [ChEMBL: CHEMBL5163] [GtoPdb: 580] [UniProtKB: Q9NY46]
  • This target only has 0 pki data point
  • 0
42 CHEMBL250699_lig_chart_42 Sodium channel protein type III alpha subunit Human
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  • Nav1.7/Sodium channel protein type IX alpha subunit in Human [ChEMBL: CHEMBL4296] [GtoPdb: 584] [UniProtKB: Q15858]
  • This target only has 0 pki data point
  • 0
43 CHEMBL250699_lig_chart_43 Sodium channel protein type IX alpha subunit Human
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  • Nav1.5/Sodium channel protein type V alpha subunit in Human [ChEMBL: CHEMBL1980] [GtoPdb: 582] [UniProtKB: Q14524]
  • This target only has 0 pki data point
  • 0
44 CHEMBL250699_lig_chart_44 Sodium channel protein type V alpha subunit Human
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  • Nav1.8/Sodium channel protein type X alpha subunit in Human [ChEMBL: CHEMBL5451] [GtoPdb: 585] [UniProtKB: Q9Y5Y9]
  • Nav1.8/Sodium channel protein type X alpha subunit in Mouse [ChEMBL: CHEMBL5158] [GtoPdb: 585] [UniProtKB: Q6QIY3]
  • Nav1.8/Sodium channel protein type X alpha subunit in Rat [ChEMBL: CHEMBL4017] [GtoPdb: 585] [UniProtKB: Q62968]
  • This target only has 0 pki data point
  • 0
45 CHEMBL250699_lig_chart_45 Sodium channel protein type X alpha subunit HumanMouseRat
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  • Translocator protein in Human [ChEMBL: CHEMBL5742] [GtoPdb: 2879] [UniProtKB: P30536]
  • This target only has 0 pki data point
  • 0
46 CHEMBL250699_lig_chart_46 Translocator protein Human
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  • TRPV1/Vanilloid receptor in Human [ChEMBL: CHEMBL4794] [GtoPdb: 507] [UniProtKB: Q8NER1]
  • This target only has 0 pki data point
  • 0
47 CHEMBL250699_lig_chart_47 Vanilloid receptor Human
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  • Cav2.2/Voltage-gated N-type calcium channel alpha-1B subunit in Human [ChEMBL: CHEMBL4478] [GtoPdb: 533] [UniProtKB: Q00975]
  • This target only has 0 pki data point
  • 0
48 CHEMBL250699_lig_chart_48 Voltage-gated N-type calcium channel alpha-1B subunit Human
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  • Kv7.2/Voltage-gated potassium channel subunit Kv7.2 in Human [ChEMBL: CHEMBL2476] [GtoPdb: 561] [UniProtKB: O43526]
  • This target only has 0 pki data point
  • 0
49 CHEMBL250699_lig_chart_49 Voltage-gated potassium channel subunit Kv7.2 Human
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  • Kv7.3/Voltage-gated potassium channel subunit Kv7.3 in Human [ChEMBL: CHEMBL2684] [GtoPdb: 562] [UniProtKB: O43525]
  • This target only has 0 pki data point
  • 0
50 CHEMBL250699_lig_chart_50 Voltage-gated potassium channel subunit Kv7.3 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
A1 receptor/Adenosine A1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL226] [GtoPdb: 18] [UniProtKB: P30542]
ChEMBL Displacement of [3H]DPCPX from adenosine A1 receptor B 5 pIC50 >10000 nM IC50 Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 8520-8525 [PMID:17483457]
A2A receptor/Adenosine A2a receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL251] [GtoPdb: 19] [UniProtKB: P29274]
ChEMBL Displacement of [3H]CGS-21680 from adenosine A2A receptor B 5 pIC50 10000 nM IC50 Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 8520-8525 [PMID:17483457]
A3 receptor/Adenosine A3 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL256] [GtoPdb: 21] [UniProtKB: P0DMS8]
ChEMBL Displacement of [125I]AB-MECA from adenosine A3 receptor B 4.92 pIC50 12000 nM IC50 Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 8520-8525 [PMID:17483457]
α1B-adrenoceptor/Alpha-1b adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL232] [GtoPdb: 23] [UniProtKB: P35368]
ChEMBL Displacement of [3H](-)CGP-12177 from adrenergic beta-1 receptor B 5 pIC50 >10000 nM IC50 Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 8520-8525 [PMID:17483457]
α2A-adrenoceptor/Alpha-2a adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1867] [GtoPdb: 25] [UniProtKB: P08913]
ChEMBL Displacement of [3H]RX821002 from adrenergic alpha-2 receptor B 5 pIC50 >10000 nM IC50 Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 8520-8525 [PMID:17483457]
α2B-adrenoceptor/Alpha-2b adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1942] [GtoPdb: 26] [UniProtKB: P18089]
ChEMBL Displacement of [3H](-)CGP-12177 from adrenergic beta2 receptor B 5 pIC50 >10000 nM IC50 Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 8520-8525 [PMID:17483457]
CB1 receptor/Cannabinoid CB1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554]
ChEMBL Displacement of [3H]Win 55212-2 from cannabinoid CB1 receptor B 5 pIC50 10000 nM IC50 Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 8520-8525 [PMID:17483457]
CB2 receptor/Cannabinoid CB2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972]
ChEMBL Displacement of [3H]Win 55212-2 from cannabinoid CB2 receptor B 5 pIC50 >10000 nM IC50 Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 8520-8525 [PMID:17483457]
CCR1/C-C chemokine receptor type 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2413] [GtoPdb: 58] [UniProtKB: P32246]
ChEMBL Displacement of [125I]MIP1-alpha from CCR1 receptor B 5 pIC50 >10000 nM IC50 Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 8520-8525 [PMID:17483457]
CCK1 receptor/Cholecystokinin A receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1901] [GtoPdb: 76] [UniProtKB: P32238]
ChEMBL Binding affinity to CCKAR B 5.7 pIC50 >2000 nM IC50 J. Med. Chem. (2008) 51: 407-416 [PMID:18176998]
δ receptor/Delta opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143]
ChEMBL Displacement of [3H]DADLE from opioid delta receptor B 5 pIC50 >10000 nM IC50 Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 8520-8525 [PMID:17483457]
D1 receptor/Dopamine D1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2056] [GtoPdb: 214] [UniProtKB: P21728]
ChEMBL Displacement of [3H]SCH-23390 from dopamine D1 receptor B 5.15 pIC50 7000 nM IC50 Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 8520-8525 [PMID:17483457]
ChEMBL Binding affinity to dopamine D1 receptor B 5.7 pIC50 >2000 nM IC50 J. Med. Chem. (2008) 51: 407-416 [PMID:18176998]
D2 receptor/Dopamine D2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416]
ChEMBL Displacement of [3H]spiperone from dopamine D2 receptor B 5