glembatumumab vedotin   

GtoPdb Ligand ID: 8926

Synonyms: CDX-011 | CR011-vcMMAE
Compound class: Antibody
Comment: Glembatumumab vedotin is a fully human anti-gpNMB (transmembrane glycoprotein NMB; gene symbol GPNMB) monoclonal antibody-drug conjugate (ADC) carrying the antineoplastic toxin monomethyl auristatin E (MMAE; PubChem CID 11542188). Development and preclinical evaluation of this ADC is reported in [4].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
10123 glembatumumab vedotin
Synonyms
CDX-011 | CR011-vcMMAE
Comments
Glembatumumab vedotin is a fully human anti-gpNMB (transmembrane glycoprotein NMB; gene symbol GPNMB) monoclonal antibody-drug conjugate (ADC) carrying the antineoplastic toxin monomethyl auristatin E (MMAE; PubChem CID 11542188). Development and preclinical evaluation of this ADC is reported in [4].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Database Links
Specialist databases
IMGT/mAb-DB 565
Other databases
GtoPdb PubChem SID 310264707
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Wikipedia Glembatumumab vedotin