TRULI [Ligand Id: 12663] activity data from GtoPdb

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  • large tumor suppressor kinase 1 in Human [GtoPdb: 1515] [UniProtKB: O95835]
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  • large tumor suppressor kinase 2 in Human [GtoPdb: 1516] [UniProtKB: Q9NRM7]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
large tumor suppressor kinase 1 in Human [GtoPdb: 1515] [UniProtKB: O95835]
GtoPdb LATS1 inhibition at 10 μM ATP - 9.7 pIC50 0.2 nM IC50 Nat Commun (2021) 12: 3100 [PMID:34035288]
large tumor suppressor kinase 2 in Human [GtoPdb: 1516] [UniProtKB: Q9NRM7]
GtoPdb LATS2 inhibition at 10 μM ATP - 9.7 pIC50 0.2 nM IC50 Nat Commun (2021) 12: 3100 [PMID:34035288]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.