alfuzosin   Click here for help

GtoPdb Ligand ID: 7109

Synonyms: SL-77499-10 | SL-7749910 | Uroxatral®
Approved drug
alfuzosin is an approved drug (FDA (2003))
Compound class: Synthetic organic
Comment: Alfuzosin is an α1-adrenergic receptor antagonist.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 116.05
Molecular weight 389.21
XLogP 3.04
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES COc1cc2nc([nH]c(=N)c2cc1OC)N(CCCN=C(C1CCCO1)O)C
Isomeric SMILES COc1cc2nc([nH]c(=N)c2cc1OC)N(CCCN=C(C1CCCO1)O)C
InChI InChI=1S/C19H27N5O4/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23)
InChI Key WNMJYKCGWZFFKR-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (2003))
IUPAC Name Click here for help
N-{3-[(4-imino-6,7-dimethoxy-3,4-dihydroquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboximidic acid
International Nonproprietary Names Click here for help
INN number INN
5357 alfuzosin
Synonyms Click here for help
SL-77499-10 | SL-7749910 | Uroxatral®
Database Links Click here for help
CAS Registry No. 81403-80-7
ChEMBL Ligand CHEMBL709
DrugBank Ligand DB00346
DrugCentral Ligand 115
GtoPdb PubChem SID 178103686
PubChem CID 2092
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Wikipedia Alfuzosin