GSK329 [Ligand Id: 11806] activity data from GtoPdb

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  • B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056]
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  • TNNI3 interacting kinase in Human [GtoPdb: 2247] [UniProtKB: Q59H18]
  • TNNI3 interacting kinase in Mouse [GtoPdb: 2247] [UniProtKB: Q5GIG6]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056]
GtoPdb - - 5.7 pIC50 >2000 nM IC50 J Med Chem (2021) 64: 15651-15670 [PMID:34699203]
TNNI3 interacting kinase in Human [GtoPdb: 2247] [UniProtKB: Q59H18]
GtoPdb - - 9.27 pKi 0.54 nM Ki J Med Chem (2021) 64: 15651-15670 [PMID:34699203]
GtoPdb - - 8 pIC50 10 nM IC50 J Med Chem (2021) 64: 15651-15670 [PMID:34699203]
TNNI3 interacting kinase in Mouse [GtoPdb: 2247] [UniProtKB: Q5GIG6]
GtoPdb - - 7.89 pKi 13 nM Ki J Med Chem (2021) 64: 15651-15670 [PMID:34699203]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.