ChEMBL ligand: CHEMBL81379 (All-Trans-Retinal, Retinal)
Alpha-synuclein in Human [ChEMBL: CHEMBL6152] [UniProtKB: P37840] There should be some charts here, you may need to enable JavaScript!
Beta amyloid A4 protein in Human [ChEMBL: CHEMBL2487] [UniProtKB: P05067] There should be some charts here, you may need to enable JavaScript!
CNGA2 in Rat [GtoPdb: 395] [UniProtKB: Q00195] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Alpha-synuclein in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6152] [UniProtKB: P37840]
ChEMBL	Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assay	B	6.72	pIC50	190	nM	IC50	Eur J Med Chem (2019) 167: 10-36 [PMID:30743095]
Beta amyloid A4 protein in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2487] [UniProtKB: P05067]
ChEMBL	Inhibition of amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assay	B	6.74	pIC50	180	nM	IC50	Eur J Med Chem (2019) 167: 10-36 [PMID:30743095]
CNGA2 in Rat [GtoPdb: 395] [UniProtKB: Q00195]
GtoPdb	-	-	4.57	pIC50	-	-	-	Proc Natl Acad Sci USA (2002) 99: 8372-7 [PMID:12034887]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]