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Compound class:
Peptide
Comment: Blisibimod is a peptibody fusion containing four BAFF binding domains fused to a human Fc domain. By sequestering circulating BAFF ligand, it acts as a functional antagonist of BAFF interaction with the TACI receptor on B cells.
Peptide sequences and structural information for this peptide are available from its IMGT/mAb-DB entry. The peptide sequence for blisibimod is claimed in Amgen's patent WO2002092620 [5]. |
Classification ![]() |
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| Compound class | Peptide |
International Nonproprietary Names ![]() |
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| INN number | INN |
| 9583 | blisibimod |
Synonyms ![]() |
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| A-623 | AGP3 peptibody [5] | AMG 623 | Fc-Agp-3 [1] | |
Database Links ![]() |
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| Specialist databases | |
| IMGT/mAb-DB | 413 |
| Other databases | |
| GtoPdb PubChem SID | 336446905 |
| Search PubMed clinical trials | blisibimod |
| Search PubMed titles | blisibimod |
| Search PubMed titles/abstracts | blisibimod |