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ChEMBL ligand: CHEMBL2108248 (ABR-214936, Anatumomab mafenatox, Anyara) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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trophoblast glycoprotein in Human [GtoPdb: 3009] [UniProtKB: Q13641] | ||||||||
GtoPdb | Binding affinity for 5T4 expressed on human Calu-1 lung cancer cells. | - | 8.92 | pKd | 1.2 | nM | Kd | Br J Cancer (2001) 85: 129-36 [PMID:11437414] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]