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ChEMBL ligand: CHEMBL2108248 (ABR-214936, Anatumomab mafenatox, Anyara, PNU-214936) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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trophoblast glycoprotein in Human [GtoPdb: 3009] [UniProtKB: Q13641] | ||||||||
GtoPdb | Binding affinity for 5T4 expressed on human Calu-1 lung cancer cells. | - | 8.92 | pKd | 1.2 | nM | Kd | Br J Cancer (2001) 85: 129-36 [PMID:11437414] |
ChEMBL data shown on this page come from version 32:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]