anatumomab mafenatox [Ligand Id: 9947] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL2108248 (ABR-214936, Anatumomab mafenatox, Anyara)
  • trophoblast glycoprotein in Human [GtoPdb: 3009] [UniProtKB: Q13641]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
trophoblast glycoprotein in Human [GtoPdb: 3009] [UniProtKB: Q13641]
GtoPdb Binding affinity for 5T4 expressed on human Calu-1 lung cancer cells. - 8.92 pKd 1.2 nM Kd Br J Cancer (2001) 85: 129-36 [PMID:11437414]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]