ethosuximide   Click here for help

GtoPdb Ligand ID: 7182

Synonyms: CI-366 | CN-10395 | PM-671 | Zarontin®
Approved drug
ethosuximide is an approved drug (FDA (1960))
Compound class: Synthetic organic
Comment: Ethosuximide is a succinimide anticonvulsant. It is often preferred over valproic acid as it does not produce the same hepatotoxicity.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 49.66
Molecular weight 141.08
XLogP 0.75
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES CC1(CC)CC(=NC1=O)O
Isomeric SMILES CC1(CC)CC(=NC1=O)O
InChI InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
InChI Key HAPOVYFOVVWLRS-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1960))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name Click here for help
3-ethyl-5-hydroxy-3-methyl-3,4-dihydro-2H-pyrrol-2-one
International Nonproprietary Names Click here for help
INN number INN
1077 ethosuximide
Synonyms Click here for help
CI-366 | CN-10395 | PM-671 | Zarontin®
Database Links Click here for help
CAS Registry No. 77-67-8
ChEMBL Ligand CHEMBL696
DrugBank Ligand DB00593
DrugCentral Ligand 1087
GtoPdb PubChem SID 178103757
PubChem CID 3291
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Wikipedia Ethosuximide