ethosuximide   Click here for help

GtoPdb Ligand ID: 7182

Synonyms: CI-366 | CN-10395 | PM-671 | Zarontin®
Approved drug
ethosuximide is an approved drug (FDA (1960))
Compound class: Synthetic organic
Comment: Ethosuximide is a succinimide anticonvulsant. It is often preferred over valproic acid as it does not produce the same hepatotoxicity.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 49.66
Molecular weight 141.08
XLogP 0.75
No. Lipinski's rules broken 0
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Canonical SMILES CC1(CC)CC(=NC1=O)O
Isomeric SMILES CC1(CC)CC(=NC1=O)O
InChI InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
Bioactivity Comments
Due to the complex nature of this drug's MMOA, and the paucity of (human) affinity data, we do not tag a primary drug target.