mitemcinal [Ligand Id: 3511] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL1778156
  • motilin receptor/Motilin receptor in Human [ChEMBL: CHEMBL2203] [GtoPdb: 297] [UniProtKB: O43193]
  • motilin receptor in Rabbit [GtoPdb: 297]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
motilin receptor/Motilin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2203] [GtoPdb: 297] [UniProtKB: O43193]
ChEMBL Antagonist activity at MLNR (unknown origin) B 8.4 pIC50 3.98 nM IC50 J Med Chem (2013) 56: 1197-1210 [PMID:23281966]
motilin receptor in Rabbit [GtoPdb: 297]
GtoPdb - - 8.2 pIC50 - - - Clin Exp Pharmacol Physiol (1999) 26: 242-5 [PMID:10081621]
GtoPdb - - 7.8 pEC50 - - - Pharmacology (2007) 79: 137-48 [PMID:17183187];
Bioorg Med Chem Lett (1994) 4: 1347-1352

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]