mitemcinal   Click here for help

GtoPdb Ligand ID: 3511

Synonyms: GM-611 | GM611
Compound class: Synthetic organic
Comment: Mitemcinal is a non-peptide, orally active motilin receptor agonist that was developed by Chugai Pharmaceutical [6] as a prokinetic agent for the treatment of gastroparesis [5,7].
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 13
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 151.68
Molecular weight 755.48
XLogP 2.66
No. Lipinski's rules broken 1
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Isomeric SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@H]([C@]2(OC(=C(C)C2)[C@@H](C(=O)[C@]1(C)OC)C)C)O[C@@H]1O[C@H](C)C[C@@H]([C@H]1O)N(C(C)C)C
InChI InChI=1S/C40H69NO12/c1-16-28-40(12,47-15)33(43)23(6)31-21(4)18-39(11,53-31)35(52-37-30(42)27(17-22(5)48-37)41(13)20(2)3)24(7)32(25(8)36(45)50-28)51-29-19-38(10,46-14)34(44)26(9)49-29/h20,22-30,32,34-35,37,42,44H,16-19H2,1-15H3/t22-,23+,24+,25-,26+,27+,28-,29+,30-,32+,34+,35-,37+,38-,39+,40-/m1/s1
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
8171 mitemcinal
Synonyms Click here for help
GM-611 | GM611
Database Links Click here for help
Specialist databases
GPCRdb Ligand mitemcinal
Other databases
CAS Registry No. 154738-42-8 (source: Scifinder)
ChEMBL Ligand CHEMBL1778156
GtoPdb PubChem SID 178100497
PubChem CID 177964
Search Google for chemical match using the InChIKey BELMMAAWNYFCGF-AQBNEDITSA-N
Search Google for chemicals with the same backbone BELMMAAWNYFCGF
Search PubMed clinical trials mitemcinal
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UniChem Compound Search for chemical match using the InChIKey BELMMAAWNYFCGF-AQBNEDITSA-N
UniChem Connectivity Search for chemical match using the InChIKey BELMMAAWNYFCGF-AQBNEDITSA-N
Wikipedia Mitemcinal