levonorgestrel [Ligand Id: 2881] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL1389 (Levonelle-2, Levonorgestrel component of marlissa, Upostelle, Emerres, NSC-744007, Levonorgestrel component of afirmelle, Fallback solo, Norplant, Athentia next, Levonorgestrel component of loseasonique, Plan b one-step, Ezinelle, Levonorgestrel component of triphasil, Levonorgestrelum, Levonorgestrel component of trivora, Levonorgestrel component of enpresse, Postinor-2, Levonorgestrel component of kurvelo, Opcicon one-step, BAY86-5028, Levonorgestrel component of opcicon one-step, Kyleena, Norgeston, Levonorgestrel component of vienva, Jadelle, Levonelle, Levonorgestrel component of orsythia, Norgestrel, (-)-, Levonorgestrel component of quartette, WY-5104, Levonorgestrel component of preven, Levonorgestrel component of elifemme, Mirena, Norgestrel (-)-form, Levonorgestrel component of aviane, Levonorgestrel component of climara pro, Levonorgestrel component of setlakin, Isteranda, Liletta, Levonorgestrel component of lybrel, Microval, Jaydess, Norplant ii, Levonorgestrel component of introvale, Levonorgestrel component of levora, Levonorgestrel component of twirla, Levonorgestrel component of seasonale, Levonorgestrel component of portia, Levonorgestrel component of myzilra, Levonorgestrel component of alesse, Levonorgestrel component of lessina, Levonorgestrel component of altavera, Levonorgestrel component of kyleena, Levonorgestrel component of balcoltra, Levonorgestrel component of levonest, Levonelle one step, Levonorgestrel component of nordette, Plan b, Levonorgestrel component of levlite, Her style, Levosert, Skyla, Emerres una, Levonorgestrel component of tyblume, Levonorgestrel component of quasense, Levonorgestrel component of seasonique, Levonorgestrel)
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Progesterone receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL208] [GtoPdb: 627] [UniProtKB: P06401]
ChEMBL Agonist activity at human PR-alpha expressed in U2OS cells by PathHunter assay B 9 pEC50 1 nM EC50 J Med Chem (2022) 65: 9974-10000 [PMID:35797110]
ChEMBL Agonist activity at human PR-beta expressed in U2OS cells by PathHunter assay B 9 pEC50 1 nM EC50 J Med Chem (2022) 65: 9974-10000 [PMID:35797110]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]