ChEMBL ligand: CHEMBL1389 (Athentia next, BAY86-5028, Emerres, Emerres una, Ezinelle, Fallback solo, Her style, Isteranda, Jadelle, Jaydess, Kyleena, Levonelle, Levonelle-2, Levonelle one step, Levonorgestrel, Levonorgestrelum, Levosert, Liletta, Microval, Mirena, Norgeston, Norgestrel, (-)-, Norgestrel (-)-form, Norplant, Norplant Ii, Norplant System, NSC-744007, Opcicon one-step, Ovrette, Plan B, Plan b one-step, Postinor-2, Skyla, Upostelle, WY-5104)

Progesterone receptor in Human [ChEMBL: CHEMBL208] [GtoPdb: 627] [UniProtKB: P06401] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Progesterone receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL208] [GtoPdb: 627] [UniProtKB: P06401]
ChEMBL	Agonist activity at human PR-alpha expressed in U2OS cells by PathHunter assay	B	9	pEC50	1	nM	EC50	J Med Chem (2022) 65: 9974-10000 [PMID:35797110]
ChEMBL	Agonist activity at human PR-beta expressed in U2OS cells by PathHunter assay	B	9	pEC50	1	nM	EC50	J Med Chem (2022) 65: 9974-10000 [PMID:35797110]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]