CP-673451 [Ligand Id: 8069] activity data from GtoPdb

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  • platelet derived growth factor receptor alpha in Human [GtoPdb: 1803] [UniProtKB: P16234]
  • This target only has 0 pki data point
1 _lig_chart_1 platelet derived growth factor receptor alpha Human
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  • platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619]
  • This target only has 0 pki data point
2 _lig_chart_2 platelet derived growth factor receptor beta Human
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  • KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721]
  • This target only has 0 pki data point
3 _lig_chart_3 KIT proto-oncogene, receptor tyrosine kinase Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
platelet derived growth factor receptor alpha in Human [GtoPdb: 1803] [UniProtKB: P16234]
GtoPdb - - 8 pIC50 10 nM IC50 Cancer Res. (2005) 65: 957-66 [PMID:15705896]
platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619]
GtoPdb - - 9 pIC50 1 nM IC50 Cancer Res. (2005) 65: 957-66 [PMID:15705896]
KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721]
GtoPdb - - 6.6 pIC50 252 nM IC50 Cancer Res. (2005) 65: 957-66 [PMID:15705896]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.