GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

beta-defensin 4A   Click here for help

GtoPdb Ligand ID: 3648

Synonyms: beta-defensin 2 | HBD2 | skin-antimicrobial peptide 1 (SAP1)
Compound class: Endogenous peptide in human, mouse or rat
Comment: Human beta-defensin 4A is an antimicrobial peptide originally identified in psoriatic skin lesions [1]. It has potent antimicrobial activity against Gram-negative bacteria and the yeast Candida albicans but not the Gram-positive Staphylococcus aureus [1].
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Synonyms Click here for help
beta-defensin 2 | HBD2 | skin-antimicrobial peptide 1 (SAP1)
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
DEFB4A defensin beta 4A Human prepro-beta-defensin 4A DEFB102, DEFB-2, DEFB2, DEFB4, defensin, beta 2, defensin, beta 4, defensin, beta 4A, HBD-2, SAP1
DEFB4B defensin beta 4B Human prepro-beta-defensin 4A DEFB4P, defensin, beta 4B, defensin, beta 4, pseudogene
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo hBD-2
GPCRdb Ligand beta-defensin 4A
Other databases
Ensembl Gene ENSG00000171711 (Hs)
GtoPdb PubChem SID 178100546
Human Protein Atlas ENSG00000171711 (Hs)
OMIM 602215 (Hs)
RefSeq Protein NP_004933 (Hs)
UniProtKB O15263 (Hs)
Wikipedia Beta-defensin_2 (Hs)