Synonyms: AVI | NXL 104 | NXL-104 | NXL104
avibactam is an approved drug (FDA (2015), EMA (2016))
Compound class:
Synthetic organic
Comment: Avibactam (NXL104) is non-β-lactam β-lactamase inhibitor [1]. It has activity against class A and C serine β-lactamases, including Klebsiella pneumoniae carbapenemases.
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Classification ![]() |
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Compound class | Synthetic organic |
Approved drug? | Yes (FDA (2015), EMA (2016)) |
WHO Essential Medicine | WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version. Click to view more information about the WHO Model Lists of Essential Medicines. |
Prodrug | avibactam tomilopil |
IUPAC Name ![]() |
[(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate |
International Nonproprietary Names ![]() |
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INN number | INN |
8972 | avibactam |
Synonyms ![]() |
AVI | NXL 104 | NXL-104 | NXL104 |
Database Links ![]() |
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Specialist databases | |
Antibiotic DB
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Avibactam (Avycaz, Zavicefta) |
Other databases | |
BindingDB Ligand | 50339145 |
CAS Registry No. | 1192500-31-4 (source: WHO INN record) |
ChEMBL Ligand | CHEMBL1689063 |
DrugCentral Ligand | 4946 |
GtoPdb PubChem SID | 405560202 |
PubChem CID | 9835049 |
RCSB PDB Ligand | FYG |
Search Google for chemical match using the InChIKey | NDCUAPJVLWFHHB-UHNVWZDZSA-N |
Search Google for chemicals with the same backbone | NDCUAPJVLWFHHB |
Search PubMed clinical trials | avibactam |
Search PubMed titles | avibactam |
Search PubMed titles/abstracts | avibactam |
UniChem Compound Search for chemical match using the InChIKey | NDCUAPJVLWFHHB-UHNVWZDZSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | NDCUAPJVLWFHHB-UHNVWZDZSA-N |