compound 12a [PMID: 29031075] [Ligand Id: 9684] activity data from GtoPdb

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  • COX-1 in Human [GtoPdb: 1375] [UniProtKB: P23219]
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  • COX-2 in Human [GtoPdb: 1376] [UniProtKB: P35354]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
COX-1 in Human [GtoPdb: 1375] [UniProtKB: P23219]
GtoPdb - - 3.98 pIC50 104000 nM IC50 Eur J Med Chem (2017) 141: 306-321 [PMID:29031075]
COX-2 in Human [GtoPdb: 1376] [UniProtKB: P35354]
GtoPdb - - 6.64 pIC50 230 nM IC50 Eur J Med Chem (2017) 141: 306-321 [PMID:29031075]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.