tirzepatide   Click here for help

GtoPdb Ligand ID: 11429

Synonyms: LY-3298176 | LY3298176
Comment: Tirzepatide (LY3298176) is a clinical stage dual GIP/GLP-1 agonist ('twincretin'), that was developed to help manage type 2 diabetes mellitus (T2DM) [1-2]. Structurally it is 39 amino acid linear peptide that is conjugated to a C20 fatty diacid moiety by a linker connected to the lysine20 residue. The dual agonist approach produces a synergetic effect on the insulin and glucagonostatic responses [1,4].
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Classification Click here for help
Compound class Peptide or derivative
International Nonproprietary Names Click here for help
INN number INN
10849 tirzepatide
Synonyms Click here for help
LY-3298176 | LY3298176
Database Links Click here for help
GtoPdb PubChem SID 440816798
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