compound 14k [PMID: 21982499]

Ligand id: 8214

Name: compound 14k [PMID: 21982499]

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	5
Hydrogen bond donors	2
Rotatable bonds	3
Topological polar surface area	79.38
Molecular weight	372.09
XLogP	5.68
No. Lipinski's rules broken	1

Molecular properties generated using the CDK

Classification
Compound class	Synthetic organic

IUPAC Name
N-(2-chlorophenyl)-7-(1H-1,2,4-triazol-5-yl)benzo[c][2,6]naphthyridin-5-amine

IUPAC Name

N-(2-chlorophenyl)-7-(1H-1,2,4-triazol-5-yl)benzo[c][2,6]naphthyridin-5-amine

Comments
Compound 14k was identified as a potent dual inhibitor of Pim1 and Pim2 [1].

Comments

Compound 14k was identified as a potent dual inhibitor of Pim1 and Pim2 [1].

Database Links
BindingDB Ligand	50357587
ChEMBL Ligand	CHEMBL1915438
GtoPdb PubChem SID	249565894
PubChem CID	44222958
Search Google for chemical match using the InChIKey	WNOHFJIMKSDPHP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	WNOHFJIMKSDPHP
Search UniChem for chemical match using the InChIKey	WNOHFJIMKSDPHP-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	WNOHFJIMKSDPHP