MS40 [Ligand Id: 12000] activity data from GtoPdb

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  • WD repeat domain 5 in Human [GtoPdb: 2831] [UniProtKB: P61964]
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  • cereblon in Human [GtoPdb: 3086] [UniProtKB: Q96SW2]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
WD repeat domain 5 in Human [GtoPdb: 2831] [UniProtKB: P61964]
GtoPdb - - 6.9 pKd 125 nM Kd Oncogene (2022) 41: 3328-3340 [PMID:35525905]
cereblon in Human [GtoPdb: 3086] [UniProtKB: Q96SW2]
GtoPdb Binding affinity for CRBN’s C-terminal thalidomide binding domain - 4.83 pKd 14800 nM Kd Oncogene (2022) 41: 3328-3340 [PMID:35525905]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.