rufinamide   Click here for help

GtoPdb Ligand ID: 7470

Synonyms: Banzel® | CGP-33101 | Inovelon® | RUF-331
Approved drug
rufinamide is an approved drug (EMA (2007), FDA (2008))
Compound class: Synthetic organic
Comment: Rufinamide is a triazole (a heterocyclic compound with molecular formula C2H3N3) derivative anticonvulsant drug.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 73.8
Molecular weight 238.07
XLogP 0.89
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES Fc1cccc(c1Cn1nnc(c1)C(=O)N)F
Isomeric SMILES Fc1cccc(c1Cn1nnc(c1)C(=O)N)F
InChI InChI=1S/C10H8F2N4O/c11-7-2-1-3-8(12)6(7)4-16-5-9(10(13)17)14-15-16/h1-3,5H,4H2,(H2,13,17)
InChI Key POGQSBRIGCQNEG-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (EMA (2007), FDA (2008))
IUPAC Name Click here for help
1-[(2,6-difluorophenyl)methyl]triazole-4-carboxamide
International Nonproprietary Names Click here for help
INN number INN
7387 rufinamide
Synonyms Click here for help
Banzel® | CGP-33101 | Inovelon® | RUF-331
Database Links Click here for help
CAS Registry No. 106308-44-5
ChEMBL Ligand CHEMBL1201754
DrugBank Ligand DB06201
DrugCentral Ligand 3534
GtoPdb PubChem SID 187051773
PubChem CID 129228
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Wikipedia Rufinamide

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Tocris
Rufinamide
Cat. No. 3828