LUT014 [Ligand Id: 11568] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056]
GtoPdb Inhibition of BRAFV600E mutant kinase - 7.88 pIC50 13.3 nM IC50 Cancer Discov (2021) 11: 2158-2167 [PMID:33910927]
GtoPdb Inhibition of wild type BRAF - 7.93 pIC50 11.7 nM IC50 Cancer Discov (2021) 11: 2158-2167 [PMID:33910927]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.