ChEMBL ligand: CHEMBL398110 (Uk-396,082, UK 396082, UK-396082)
Carboxypeptidase B1 (tissue)/Carboxypeptidase B in Human [ChEMBL: CHEMBL2552] [GtoPdb: 1593] [UniProtKB: P15086] Carboxypeptidase B in Pig [ChEMBL: CHEMBL4065] [UniProtKB: P09955] There should be some charts here, you may need to enable JavaScript!
Carboxypeptidase B2 (plasma)/Carboxypeptidase B2 isoform A in Human [ChEMBL: CHEMBL3419] [GtoPdb: 1594] [UniProtKB: Q96IY4] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Carboxypeptidase B1 (tissue)/Carboxypeptidase B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2552] [GtoPdb: 1593] [UniProtKB: P15086]
ChEMBL	Inhibition of human pancreatic carboxypeptidase B	B	6.69	pKi	206	nM	Ki	Bioorg Med Chem Lett (2010) 20: 92-96 [PMID:19954973]
Carboxypeptidase B in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4065] [UniProtKB: P09955]
ChEMBL	Inhibition of porcine pancreatic carboxypeptidase B	B	6.69	pKi	206	nM	Ki	J Med Chem (2007) 50: 6095-6103 [PMID:17990866]
Carboxypeptidase B2 (plasma)/Carboxypeptidase B2 isoform A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3419] [GtoPdb: 1594] [UniProtKB: Q96IY4]
ChEMBL	Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins	B	7.8	pKi	16	nM	Ki	Bioorg Med Chem Lett (2010) 20: 92-96 [PMID:19954973]
GtoPdb	-	-	8	pKi	10	nM	Ki	J Med Chem (2007) 50: 6095-103 [PMID:17990866]
ChEMBL	Inhibition of human TAFIa	B	8	pKi	10	nM	Ki	J Med Chem (2007) 50: 6095-6103 [PMID:17990866]
ChEMBL	Inhibition of TAF1a in human plasma assessed as clot lysis	B	5.3	pIC50	5000	nM	IC50	Bioorg Med Chem (2014) 22: 2261-2268 [PMID:24588961]
ChEMBL	Inhibition of human TAF1a using hippuryl-L-arginine/hippuryl-L-lysine as substrate by liquid chromatographic analysis	B	6.35	pIC50	450	nM	IC50	Bioorg Med Chem (2014) 22: 2261-2268 [PMID:24588961]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]