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Synonyms: EL-737 | Optaflexx® | Paylean® | ractopamin | Tomax®
Compound class: Synthetic organic
Comment: Ractopamine exhibits agonist activity at the trace amine receptor 1 (TA1)  and β-adrenoceptors [1-2].
In some countries ractopamine is used as a feed additive in commercial livestock husbandry to increase lean meat mass. This use is banned in the EU and many other countries, but is permitted in countries including the US, Canada, Mexico, Japan and South Korea. Ractopamine's effect on human physiology has not been fully characterised, so the safety of consuming trace ractopamine in meat from treated animals remains controversial.
Commercially used ractopamine is administered as the hydrochloride salt and is a racemic mixture of all 4 possible stereoenantiomers. We show the structure without specified stereochemistry to represent the mixture.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|Compound class||Synthetic organic|
|International Nonproprietary Names|
|EL-737 | Optaflexx® | Paylean® | ractopamin | Tomax®|
|CAS Registry No.||97825-25-7 (source: WHO INN record)|
|GtoPdb PubChem SID||385612215|
|Search Google for chemical match using the InChIKey||YJQZYXCXBBCEAQ-UHFFFAOYSA-N|
|Search Google for chemicals with the same backbone||YJQZYXCXBBCEAQ|
|Search PubMed clinical trials||ractopamine|
|Search PubMed titles||ractopamine|
|Search PubMed titles/abstracts||ractopamine|
|Search UniChem for chemical match using the InChIKey||YJQZYXCXBBCEAQ-UHFFFAOYSA-N|
|Search UniChem for chemicals with the same backbone||YJQZYXCXBBCEAQ|