2-pyridylethylamine [Ligand Id: 1197] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL32813 (2-(2-Aminoethyl)Pyridine)
  • H1 receptor/Histamine H1 receptor in Human [ChEMBL: CHEMBL231] [GtoPdb: 262] [UniProtKB: P35367]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
H1 receptor/Histamine H1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL231] [GtoPdb: 262] [UniProtKB: P35367]
GtoPdb - - 3.7 pKi - - - Eur J Biochem (2004) 271: 2636-46 [PMID:15206929]
ChEMBL Inhibitory activity against human Histamine H1 receptor B 5.9 pIC50 1258.93 nM IC50 J. Med. Chem. (2003) 46: 5812-5824 [PMID:14667234]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]