GSK2239633A

Ligand id: 10416

Name: GSK2239633A

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 159.17
Molecular weight 548.1
XLogP 2.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[[3-[[3-[(5-chlorothiophen-2-yl)sulfonylamino]-4-methoxyindazol-1-yl]methyl]phenyl]methyl]-2-hydroxy-2-methylpropanamide
Synonyms
compound 6 [PMID: 23409871] | GSK-2239633A
Comments
GSK2239633A is a arylsulfonamide class CC-chemokine receptor 4 (CCR4) antagonist. It binds the intracellular domain of the receptor, and therefore has an allosteric mode of action [2].
Database Links
BindingDB Ligand 50380880
CAS Registry No. 1240516-71-5 (source: PubChem)
ChEMBL Ligand CHEMBL2018969
GtoPdb PubChem SID 385612176
PubChem CID 46861584
Search Google for chemical match using the InChIKey YTEVTHHGQMUPHC-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YTEVTHHGQMUPHC
Search UniChem for chemical match using the InChIKey YTEVTHHGQMUPHC-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YTEVTHHGQMUPHC